This document shows how to check the certificate and connection when problems exist.
When Load Runner (LR) sends a request to the HTTPS Server on Replay, the server respond with an error about the SSL. For Web Service this error shows like this:
Action.c(4): t=2178ms: Closed connection  to xxx:2443 after completing 0 requests [MsgId: MMSG-26000]
Action.c(4): Warning -26000: Empty or no response for URL="https://xxx:2443/websrv_cdisi/V1_0/IssuerBIDLookupService" [MsgId: MWAR-26000]
Action.c(4): Error: SSL protocol error when attempting to connect with host "xxx"
Action.c(4): Error: SOAP request "SOAP Request" execution failed
As you can see, the port used by the customer is not a default 443 port.
You need to check that the certificate was binding to this port or default port. For more information http://msdn.microsoft.com/en-us/library/ms733791.aspx
Try to check the certificate and connection using openssl with this sentence from CMD:
openssl s_client -connect <server ip>:2443
openssl s_client -connect <server ip>:443
This will show the certificate information. If not, customer has a certificate problem and need to check with IT engineers.