Security Manager 6.0
Security Manager 6.5
The NetIQ Security Manager service or NqSmLm.EXE on the central computer is not started or is not responding. Please wait a few moments, and then resubmit the query. If you continue to have problems please restart the NetIQ Security Manager service on the central computer.
In order to resolve this issue, restart the NetIQ Security Manager service on the Central Computer. If the problem persists, this is likely caused by a performance issue with regards to your SQL implementation.
This article goes into great detail about how to troubleshoot SQL Server performance in SQL Server 2005:
This is typically caused by the NqSmLm.exe process becoming unresponsive and hanging, likely due to SQL connectivity.