GroupWise GWIA is not able to form an SSL connection to any other SMTP server

The GroupWise GWIA (GroupWise Internet Agent) is not able to form an SSL connection with other SMTP servers on the internet that are also setup to use and SSL certificate.  This occurs with a valid self signed certificate and also a valid commercial SSL certificate.

It was discovered that the firewall had a setting once disabled, the problem went away.  This setting is called "SMTP Inspection" .