Novell ZENworks Full Disk Encryption 11.4
After a shutdown, the Lenovo X250 would not present the PBA Logon screen until the laptop was restarted.
Updating the "USB 3.0 Driver: IntelÂ® USB 3.0 eXtensible Host Controller Driver for IntelÂ® 8/9/100 Series and C220/C610 Chipset Family" drivers to Version 22.214.171.124 resolved the issue. (Dated Jan 28th 2016)
As of the date of the writing of this TID, the latest version of the drivers can be found here: https://downloadcenter.intel.com/download/22824/USB-3-0-Driver-Intel-USB-3-0